A consultant neurologist in Oxford and Professor in the Nuffield. Department of Clinical Neurosciences, Oxford University. She runs a national service for neuromyelitis optica service (NMO) and congenital myasthenic syndromes (CMS). She has been a UK lead for the National Risk Sharing Scheme which assessed the long-term effectiveness for disease modifying agents in multiple sclerosis, is on a board of directors for the European Charcot Foundation, a member of the International Clinical Consortium of the Guthy Jackson Foundation Charity, on the Medical Advisory Board of the Sumaira Foundation Charity and the MOG project, on the Editorial Advisory Board for The Lancet Neurology, Associate Editor in Frontiers in Neurology (Multiple Sclerosis and Neuroimmunology) and is a member of MAGNIMS. In May 2025 awarded ABN Medal.